Lecture 1. Brief introduction to basic molecular biology, DNA sequence data, and the coalescent. Mutation in the coalescent.  (Tavaré )

　

Lecture 2. Models of DNA sequence evolution and estimation of evolutionary distances.  (Li)

　

Lecture 3. Methods of phylogenetic reconstruction. (Li)

　

Lecture 4. Topics in evolutionary genomics. (Li)

　

Lecture 5. Inference in the coalescent: rejection methods, importance sampling, and Markov chain Monte  
              Carlo. (Tavaré )

　

Lecture 6. Probabilistic approaches: the age of a unique event polymorphism. (Tavaré )

　

Lecture 7. Hidden Markov Models (Lu)

　

Lecture 8. Recombination and linkage disequilibrium. (Tavaré )

　

Lecture 9. Methods for detecting natural selection from sequence data. (Li)

　

Lecture 10. Inference for branching processes: estimating the age of a tumor, and the structure of a colon 
                crypt. (Tavaré )

　

Lecture 11. Species trees: using the fossil record to estimate the divergence time of species. (Tavaré )

　

Lecture 12. Methods for aligning genomic sequences. (Shih)

　

Lecture Note:

 
Simon Tavaré (1) ---------    Ancestral Inference in Molecular  Biology  (pdf file)

Simon Tavaré (2) ---------- (pdf file)

Simon Tavaré (3) ---------- (pdf file)

Simon Tavaré (4) ---------- (pdf file)

Simon Tavaré (5) ---------- (pdf file)

Simon Tavaré (6) ---------- (pdf file)

Simon Tavaré (7) ---------- (pdf file)

Simon Tavaré (8) ---------- (pdf file)